Ativan is a non-proprietary medication used in the treatment of severe anxiety. The treatment lasts for a few weeks and the dosage is increased steadily depending upon the individual. At the time of discontinuation too, the dosage is reduced gradually. Given below are the ingredients of Ativan and how they are used in pharmaceutical preparations:
Lorazepam – This is the main and also the active ingredient of Ativan. It is a kind of medicine known as benzodiazepines, used for their sedative and muscle relaxing effect and as an antianxiety medication. When a dose of Ativan is taken, the lorazepam works on GABA receptors in the brain, causing the release of chemicals that act as calming agents.
When the nerve activity in the brain is held in check, there is a decrease in anxiety; the muscles relax, inducing sleepiness in the individual. Lorazepam is used to treat severe cases of anxiety, cases of insomnia and is also used as a sedative in some patients. The effect of the drug lasts for 6-8 hours after use. Other Ingredients There are 40 categories of additives listed by the FDA, which can be used as inactive ingredients in pharmaceutical preparations. The four inactive ingredients used in the preparation of Ativan are among the 40 listed ingredients.
Lactose Monohydrate – Lactose is present in milk and has been identified as sugar. It is used in pharmaceutical preparations, where its addition to tablets to be used as filler and for its compressibility.
Magnesium Stearate – Magnesium stearate is used as a binding agent for the tablet. Its function in the medical formulation is to prevent the different molecules of the formulation from forming into lumps.
Microcrystalline Cellulose – This is used in the medication for its compressing properties. Its function in the tablet is as an emulsifier, dispersing agent and as a stabilizer.
Polacrilin Potassium – This is one of the listed additives, which is permissible for use in a pharmaceutical formulation.
All the mentioned ingredients combine to form Ativan, though it is only Lorazepam, which acts to calm down the individual and relieve him or her of anxiety. However, doctors warn that there should be no consumption of alcohol when the patient is using lorazepam. Consult your doctor about the dosage and talk to him frankly if you have any medical problems so that he can recommend the correct dosage that is required for you.